Weight Loss Lowers Cancer Risks in Postmenopausal Women

Jul 25, 2012 by

Interestingly, this article explains the direct correlation of obesity and increased cancer risk, and how this risk is markedly reduced after a period of weight loss.

Not a stretch to think this is so, especially as we are all aware of the health risks that are intensified when coupled with a state of obesity.

It's always a recommended route to consider a weight loss plan to address excessive weight concerns or obesity, which ultimately will reap some major health benefits.  Its of particular benefit for menopausal women, which studies suggest are greater cancer risk candidates, as reported in the below study.

Also intersting to note that the inflammation markers talked about can be reduced without pharmaceutical means by applying a combination of exercise and diet to shed the weight neceseary to lower the overall risk potential.


Weight loss lowers cancer risks in postmenopausal women

Weight loss lowers cancer risks in postmenopausal women

Menopausal women who were overweight or obese and lost at least 5 percent of their body weight had a measurable reduction in markers of inflammation, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

"Both obesity and inflammation have been shown to be related to several types of cancer, and this study shows that if you reduce weight, you can reduce inflammation as well," said Anne McTiernan, M.D., Ph.D., director of the Prevention Center at the Fred Hutchinson Cancer Research Center in Seattle, Wash.

Women in the trial who were assigned to a weight loss intervention had a goal of 10 percent weight reduction during the course of one year achieved through a diet intervention with or without aerobic exercise.

"So this program was highly achievable and reproducible. We are not talking about drastic weight loss," said McTiernan.

The researchers measured levels of C-reactive protein, serum amyloid A, interleukin-6, leukocyte and neutrophil in 439 women.

At the end of one year, C-reactive protein reduced by 36.1 percent in the diet-alone group and by 41.7 percent in the diet and exercise group. Interleukin-6 decreased by 23.1 percent in the diet group and 24.3 percent in the diet and exercise group.

McTiernan and colleagues found a mild dose response, as there were greater reductions in these measures among women who lost at least 5 percent of their body weight. They also found that exercise alone, without a dietary weight loss component, had little effect on inflammation markers.

"This study adds to the growing understanding we have about the link between obesity and cancer, and it appears we can affect inflammation directly through nonpharmaceutical means," said McTiernan.

Source: American Association for Cancer Research


Original Article Here



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